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Hi Gesine, if you can provide some more info about the granuloma and some therapy approaches so far, that could help me provide you with some more information.
However, you can find some good general information with our article Eosinophilic Granuloma Complex in Cats.
Essentially, an eosinophilic granuloma is related to some kind of allergy response. The allergy itself can be a number of things from something environmental to being connected to a food allergy. Some eosinophilic granulomas pop up because of a single isolated allergy response while others are due to chronic recurrence.
Usually we treat these initially with a steroid like prednisolone combined with an antibiotic. A lot of times the lesions have secondary infection present that makes them more irritating.
Sometimes if they’re from an isolated cause, a course of steroids will resolve them. The allergy cause is still present and the granuloma returns, one approach is with long-term medication like cyclosporine (Atopica) to suppress the immune response.
Allergy testing is sometimes helpful, although you can’t always intervene against the allergen if it’s a common one like dust or storage mites in the home. Elimination or prescription diet trials can also help to determine if a food allergy is related.